The pharmaceutical industry’s demand for continuous processes is increasing because it offers clear advantages such as cost savings, process robustness and no scale-up hurdles. Continuous dry granulation is now often the process of choice for large-volume or moisture-sensitive products. L.B. Bohle meets this growing demand by offering the new Bohle BRC 100, an innovative variable gap dry granulator. With the introduction of the BRC 100, L.B. Bohle now serves customer needs for all available granulation techniques in the industry.
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The Bohle BRC 100 – Dry Granulator
The BRC 100 enables high-production capacity with minimal loss of material. This is achieved by fast and precise control of the compaction force with a new electromechanical spindle drive for the two rollers. In combination with a sensitive control of the variable gap via the screw feeding system, constant ribbon properties are assured over a wide production range from <1 kg up to 200 kg/h.
Sophisticated equipment design facilitates easy handling and shortens mounting procedures during working shifts. A hygienic design and properly integrated cleaning nozzles allow an effective wash in place process (WIP).
The BRC 100 achieves ribbon granulation with the Bohle Turbo Sieve (BTS 200). The conical sieve design allows gentle particle size reduction at low sieve speeds, which is also applicable at high material throughputs. A variety of different sieve types make it flexible for different product and ribbon properties.
The BRC 100 meets Quality by Design requirements with its functional GMP design,, as well as with its ability to implement different PAT tools.
Bohle BRC 100 – Dry Granulator
Bohle BRC 100 – Dry Granulator
The pharmaceutical industry’s demand for continuous processes is increasing because it offers clear advantages such as cost savings, process robustness and no scale-up hurdles. Continuous dry granulation is now often the process of choice for large-volume or moisture-sensitive products. L.B. Bohle meets this growing demand by offering the new Bohle BRC 100, an innovative variable gap dry granulator. With the introduction of the BRC 100, L.B. Bohle now serves customer needs for all available granulation techniques in the industry.
(double click on picture)
The Bohle BRC 100 – Dry Granulator
The BRC 100 enables high-production capacity with minimal loss of material. This is achieved by fast and precise control of the compaction force with a new electromechanical spindle drive for the two rollers. In combination with a sensitive control of the variable gap via the screw feeding system, constant ribbon properties are assured over a wide production range from <1 kg up to 200 kg/h.
Sophisticated equipment design facilitates easy handling and shortens mounting procedures during working shifts. A hygienic design and properly integrated cleaning nozzles allow an effective wash in place process (WIP).
The BRC 100 achieves ribbon granulation with the Bohle Turbo Sieve (BTS 200). The conical sieve design allows gentle particle size reduction at low sieve speeds, which is also applicable at high material throughputs. A variety of different sieve types make it flexible for different product and ribbon properties.
The BRC 100 meets Quality by Design requirements with its functional GMP design,, as well as with its ability to implement different PAT tools.
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