To face the challenge of ever-increasing safety requirements and operator protection from active pharmaceutical ingredients, LB Bohle has designed the Bohle BFC 5 laboratory coater for contained coating applications. The BFC 5 coater’s versatile design allows for simple integration of isolator technology (glove box) thereby ensuring operator safety during the handling of toxic / potent substances. For applications where the product is not hazardous, the BFC 5 can be used without an isolator.
The BFC 5 includes two different sized coating pans (for either 5 or 10 kg batches) which are easily interchanged. With the optional divider plate installed, batches as small as 500 grams are possible.
The BFC 5 laboratory coater provides secure scale up results to all larger LB Bohle machines like the Bohle Film Coater BFC or the Bohle Tablet Coater BTC. The BFC 5 is a mobile coating unit that contains all technical modules, such as the complete air handling system and electrical cabinet, in its housing. Using a patented, through-the-tablet-bed air flow design within the coater, the BFC 5 significantly minimizes spray drying and the loss of coating suspension resulting in a highly efficient and effective coating process. The geometry of the coating pan and the integrated double-helix mixing spirals lead to superior mixing of the cores with the gentlest handling possible. The design allows for a fully automated discharge cycle, resulting in no tablets left in the pan.
The spray arm containing the spray nozzle assembly is mounted to the front door. By opening this door, the two nozzles are easily accessible for inspection or maintenance. The spray gun angle and bed distance can be adjusted without opening the front door of the coater. A completely welded housing minimizes edges and corners to ensure easy cleanability.
The isolator (glove box), supported by a frame with castors, is easily implemented into the BFC 5. The isolator is equipped with four (4) gloves, made of FDA-approved materials, for ergonomic handling within the chamber. A rapid transfer port (RTP) is incorporated on the isolator to facilitate contained material transfer to and from the isolator and coater.
Adjustments to the coater (nozzles, sampling, and all other manual actions during coating) can be done via the isolator. An internal spray wand is provided in the isolator for cleaning / rinsing of the isolator inner surfaces. In conjunction with the internal isolator spray device, the BFC 5 can be equipped with a simple washing system to wet all surfaces inside the pan and pan housing. After washing the coater and isolator, the isolator can be simply disconnected and removed for further cleaning of both devices if required.
Bohle Laboratory Coater
L. B. Bohle BFC 5 Laboratory Coater
To face the challenge of ever-increasing safety requirements and operator protection from active pharmaceutical ingredients, LB Bohle has designed the Bohle BFC 5 laboratory coater for contained coating applications. The BFC 5 coater’s versatile design allows for simple integration of isolator technology (glove box) thereby ensuring operator safety during the handling of toxic / potent substances. For applications where the product is not hazardous, the BFC 5 can be used without an isolator.
The BFC 5 includes two different sized coating pans (for either 5 or 10 kg batches) which are easily interchanged. With the optional divider plate installed, batches as small as 500 grams are possible.
The BFC 5 laboratory coater provides secure scale up results to all larger LB Bohle machines like the Bohle Film Coater BFC or the Bohle Tablet Coater BTC. The BFC 5 is a mobile coating unit that contains all technical modules, such as the complete air handling system and electrical cabinet, in its housing. Using a patented, through-the-tablet-bed air flow design within the coater, the BFC 5 significantly minimizes spray drying and the loss of coating suspension resulting in a highly efficient and effective coating process. The geometry of the coating pan and the integrated double-helix mixing spirals lead to superior mixing of the cores with the gentlest handling possible. The design allows for a fully automated discharge cycle, resulting in no tablets left in the pan.
The spray arm containing the spray nozzle assembly is mounted to the front door. By opening this door, the two nozzles are easily accessible for inspection or maintenance. The spray gun angle and bed distance can be adjusted without opening the front door of the coater. A completely welded housing minimizes edges and corners to ensure easy cleanability.
The isolator (glove box), supported by a frame with castors, is easily implemented into the BFC 5. The isolator is equipped with four (4) gloves, made of FDA-approved materials, for ergonomic handling within the chamber. A rapid transfer port (RTP) is incorporated on the isolator to facilitate contained material transfer to and from the isolator and coater.
Adjustments to the coater (nozzles, sampling, and all other manual actions during coating) can be done via the isolator. An internal spray wand is provided in the isolator for cleaning / rinsing of the isolator inner surfaces. In conjunction with the internal isolator spray device, the BFC 5 can be equipped with a simple washing system to wet all surfaces inside the pan and pan housing. After washing the coater and isolator, the isolator can be simply disconnected and removed for further cleaning of both devices if required.
For more information, please visit:
https://edir.bulk-online.com/profile/9613-l-b-bohle.htm
http://www.google.com/search?client=...UTF-8&oe=UTF-8
Attachments
l.b.bohle (JPG)
■